N-Acetyl Cysteine
N-Acetyl-L-Cysteine (NAC) is a precursor to glutathione, the body’s master antioxidant, supporting detoxification and cellular defence.
Female Fertility
NAC promotes the production of glutathione, a powerful intracellular antioxidant that supports oocyte quality and protects against oxidative damage. It also contributes to healthy cervical mucus production and hormonal balance. NAC is commonly used in fertility programmes for women with PCOS, endometriosis, or elevated oxidative stress markers.
Male Fertility
NAC contributes to male reproductive health by enhancing antioxidant capacity, particularly through its role in producing glutathione, a key molecule in protecting sperm from oxidative stress. It may improve sperm concentration, motility and morphology in men with suboptimal semen parameters, and is often used in antioxidant blends to support DNA integrity and mitochondrial function.
Pregnancy
During pregnancy, NAC supports maternal detoxification pathways and protects against oxidative damage. Its ability to regenerate glutathione may help reduce inflammation and support the body’s natural defences during gestation. It has also been studied for its potential to support placental health and manage oxidative stress-related complications, though further research is ongoing. NAC is well tolerated and often used as a supportive nutrient during the first and second trimesters.
