An important update: On 12 May 2026, an international consensus published in The Lancet renamed Polycystic Ovary Syndrome (PCOS) to Polyendocrine Metabolic Ovarian Syndrome (PMOS), better reflecting its hormonal and metabolic nature. The new name will be adopted by the World Health Organization's International Classification of Diseases by 2028, with both names used during the transition. Read our explainer on what the rename means for your hormones and fertility.
Polycystic Ovary Syndrome (PCOS), now also known as Polyendocrine Metabolic Ovarian Syndrome (PMOS) following a 2026 global consensus published in The Lancet, is a hormonal and metabolic disorder that affects around 1 in 8 women of reproductive age. It can cause a range of symptoms and challenges, but with the right information and management, it is possible to reduce your symptoms and live well with PCOS.
1. What is PCOS (PMOS)?
PCOS is a hormonal disorder that affects the ovaries and can disrupt the normal menstrual cycle. It is characterized by the presence of cysts on the ovaries, irregular periods, and elevated levels of androgens (male hormones) in the body. To learn more about what PCOS is, the symptoms and how to support your general wellbeing, tap here.
2. How does insulin resistance in PMOS (formerly PCOS) impact fertility?
Insulin resistance can impact fertility by disrupting ovulation and hormonal balance. Higher insulin levels can interfere with the normal hormonal signals that trigger ovulation, leading to irregular or absent menstrual cycles and reduced chances of conceiving naturally.
Additionally, insulin resistance can stimulate the ovaries to produce excess androgens, which can further disrupt ovulation by affecting the development of ovarian follicles. Lifestyle changes, such as maintaining a healthy diet, regular exercise, and weight management, along with medication if needed, may be necessary to manage insulin resistance and improve fertility outcomes for those with PCOS.
3. Can PCOS (PMOS) affect the quality of eggs or embryos in fertility treatments?
PCOS is associated with hormonal imbalances that can impact the maturation and development of eggs in the ovaries. This may result in lower quality eggs, which can affect the success rate of fertility treatments, such as in vitro fertilization (IVF) or other assisted reproductive technologies.
PCOS can also affect the quality of embryos formed from fertilized eggs. The hormonal imbalances in PCOS may impact the development of embryos during their crucial early stages, potentially leading to lower-quality embryos that have reduced chances of implanting and resulting in a successful pregnancy.
However, there are a number of things you can do to improve your egg quality. Tap here to learn more.
4. Are there specific fertility medications or protocols for women with PMOS (formerly PCOS)?
Yes, PCOS can be managed through lifestyle changes, medication, and other interventions. Treatment options may include hormonal birth control to regulate menstrual cycles, anti-androgen medications to reduce excess hair growth, and medications to manage insulin resistance.
Supplements can help support your symptom management. For those with irregular periods, we recommend Zita West Inositol & Folate. Myo-inositol is found in virtually every tissue in our body and is involved in several processes. It plays a significant role in various processes associated with reproduction including gametes development, oocyte maturation, reproduction and foetal development. Studies have shown that myo-inositol can improve reproductive outcomes for those with PCOS.
We also recommend Zita West Psyllium Husk. Insulin resistance for those with PCOS can trigger the ovaries to overproduce androgen hormones. Studies have shown that fibre can help to maintain a healthy weight, reduce the risk of insulin resistance and feed the friendly bacteria in your gut microbiome. These three factors all play an important role in promoting better fertility. Lifestyle changes, such as maintaining a healthy diet, regular exercise, and weight management, can also be effective in managing PCOS symptoms.
5. What are the lifestyle factors that can impact fertility in PCOS (PMOS)?
PCOS can be managed through lifestyle changes, medication, and other interventions. Treatment options may include hormonal birth control to regulate menstrual cycles, anti-androgen medications to reduce excess hair growth, and medications to manage insulin resistance. Lifestyle changes, such as maintaining a healthy diet, regular exercise, and weight management, can also be effective in managing PCOS symptoms. To learn more about how lifestyle can impact your PCOS symptoms, and how small changes can make a big difference, tap here.
6. How does PMOS (formerly PCOS) impact the success rate of in vitro fertilization (IVF) or other fertility procedures?
PCOS can potentially impact the success rate of in vitro fertilization (IVF) or other fertility procedures. PCOS is associated with hormonal imbalances that can affect the maturation and development of eggs in the ovaries, potentially leading to lower quality eggs. This can impact the success of IVF, as the quality of eggs is a crucial factor in the success of fertilization and embryo development. However, there are a number of ways that you can set yourself up for success through nutrition, lifestyle and mindset. PCOS is a common hormonal disorder that can cause a range of symptoms and challenges. However, with proper management, many with PCOS are able to live well and achieve their fertility goals.